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- Featured Technology
TCR Cell Therapy Targeting MAGE-A1
High-affinity MAGE-A1-specific TCR for the treatment of multiple myeloma and solid tumors.
Stage: IND enabling
Type: Cell Therapy, Therapeutic
Categories: Immuno Oncology, Target
- Featured Technology
Therapeutic peptide and biomarkers for castration-resistant prostate cancer (CRPC)
Synthetic peptide targeting PRAC1 has been developed for the treatment of CRPC.
Stage: Preclinical in vivo data available
Type: Diagnostic, Therapeutic
Categories: Biomarker, Protein / Peptide, Target
Immunotherapy for the Treatment of Obesity
A method for using immunotherapy to identify, target and eliminate fat cells.
Stage: Preclinical in vitro, Preclinical in vivo
Type: Cell Therapy, Therapeutic, Gene Therapy
Categories: HSC Therapy
Targeting Runx3 for the Treatment of Pancreatic Cancer
Novel therapeutic target to prevent metastasis of pancreatic cancer.
Stage: Target identification
Type: Therapeutic
Categories: Target
Gene Expression Biomarkers to Track Facioscapulohumeral Dystrophy Disease Progression
DUX4-dependent gene expression is a major molecular signature of Facioscapulohumeral Dystrophy (FSHD).
Stage: Pre-clinical in vitro, Clinical validation
Type: Diagnostic
Categories: Biomarker, Nucleic Acid
Multimerized HIV gp120s for Vaccine Development
An engineered HIV Env glycoprotein that improves antibody-recognition potential for HIV vaccine development.
Stage: Phase I clinical trial ongoing: NCT05471076
Type: Therapeutic
Categories: Protein / Peptide
cTRPs: Circular Tandem Repeat Protein Platform
Stage: Preclinical in vitro
Type: Therapeutic, Cell Therapy
Categories: Protein / Peptide
Digital Deletion Detection and QuantiSize
This method allows for measurement of rare deletions, while concurrently gathering information about size and homogeneity of the unknown template.
Stage: Preclinical in vitro
Type: Diagnostic, Research Tool
Categories: Assay / Method, Nucleic Acid
Pretargeted radioimmunotherapy for the treatment of Multiple Myeloma & B cell malignancies
Anti-CD38 and anti-BCMA bispecific antibodies deliver targeted radioimmunotherapy and avoid systemic toxicity.
Stage: Preclinical in vivo
Type: Therapeutic
Categories: Hybridoma / Antibody, Immuno Oncology, Target
NKG2D Biologic to Reduce Immune Cell Activation
A multimeric decoy to block activation of NKG2D and treat autoimmune and inflammatory diseases, and for use in vaccine development.
Stage: Preclinical in vivo, Preclinical in vitro
Type: Therapeutic, Vaccine
Categories: Protein / Peptide